Mandibular Trauma and Antibiotic Use (MANTRA)

Study Leads - Basim Dawoud and Becks Exley

Consultant Advisor - Panos Kyzas

This project was initiated in 2020, and aims to establish the risks and benefits of treating patients with mandible fractures on an outpatient basis. There is variation in practice, with some centres discharging all mandible fractures and carrying out ORIF electively and others admitting for IV antibiotics and emergent treatment. Patient preference, health economics and patient outcomes may vary between these two treatment algorithms. This project aims to use an initial survey of practice, followed by a national prospective audit, to determine current practice and inform design of a trial. 

April 2021

After breaking the 500 record barrier we are now setting the 3rd June as our closing date for new cases, giving us a grand total of 6 months worth of data.  After that collaborators will be able to amend entries to input the 30 day follow up until mid July.  Keep up all the good work for the final push!

February 2021

With over 200 records so far, the MANTRA snapshot audit is off to a flying start!! More units are reaching the required 5 records to be cited in future papers, and we are in the process of identifying the high performing units which will be invited to co-author. It’s not too late to sign your unit up (check the map to see if your unit is involved), and you can add all fractured mandibles which your unit has seen since 3rd December 2020. 


November 2020

Preliminary results of MTReC UK wide survey show variation exists across the UK with regard to use of antibiotics when managing mandibular fractures.  


Collaborators have been contacted and the process of the registering the study locally and setting up access to REDCap has begun.If you have been assigned as lead collaborator in your unit you will be require the following resources.

The collaborator information pack

Guide to help you add data to REDCap

July 2021

Data collection is complete and a big thank you to everyone who help collaborate.  Further updates with the preliminary results of the data to follow. 



  1. D. Kumar, B.E.S. Dawoud, S. Kent, MTReC, Panayiotis Kyzas. Antibiotic practices in non-condylar mandibular fractures: A Maxillofacial Trainee Research Collaborative (MTReC) UK-Wide Survey, British Journal of Oral and Maxillofacial Surgery, 2021. ISSN 0266-4356.
  2. E.S.Dawoud, S.Kent, A.Henry, J.Wareing, H.Chaudryeon, Panayiotis Kyzasg. The use of antibiotics in traumatic mandibular fractures: A systematic review and meta-analysis. British Journal of Oral and Maxillofacial Surgery. Available online 15 March 2021. DOI:

The Maxillofacial Trainee Research Collaborative

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